The High-Sensitivity C-Reactive Protein Level One Month After Bare-Metal Coronary Stenting May Predict Late Adverse Events
| Autor: | Juan-Antonio Fournier, Aurelio Cayuela, Soledad Cabezón, Carmen Delgado-Pecellín, María-Dolores Mendoza |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Percutaneous medicine.medical_treatment Prosthesis Design Revascularization Sensitivity and Specificity Postoperative Complications Predictive Value of Tests Internal medicine Coronary stent Humans Medicine Prospective Studies Myocardial infarction Survival rate biology business.industry C-reactive protein Stent General Medicine Middle Aged medicine.disease C-Reactive Protein Conventional PCI biology.protein Cardiology Female Stents business |
| Zdroj: | Revista Española de Cardiología (English Edition). 61:313-316 |
| ISSN: | 1885-5857 |
| DOI: | 10.1016/s1885-5857(08)60120-6 |
| Popis: | The significance of the high-sensitivity C-reactive protein (hs-CRP) level in percutaneous coronary interventions (PCIs) is unclear. Troponin-T and hs-CRP levels were measured before PCI, after stenting, and 8 h, 24 h, and 30 days after the procedure in 68 consecutive patients who received bare-metal stents. The study endpoints were death, nonfatal myocardial infarction, and the need for revascularization. The mean follow-up time after PCI was 16.6 months. Patients who experienced an event had higher hs-CRP levels 24 h (P=.05) and 30 days (P< .02) after stenting. The area under the receiver operating characteristic (ROC) curve at 30 days had the highest sensitivity (i.e., 80%) and specificity (i.e., 72%) for predicting an event. The 12-month event-free survival rate (Kaplan-Meier) was greater when the hs-CRP level at 30 days was < or =2.5 mg/L than when it was above this value (P=.04). Consequently, measuring the hs-CRP level 30 days after stenting may be useful for predicting late events. |
| Databáze: | OpenAIRE |
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