Ileal digestibility of dietary protein in the growing pig and adult human

Autor: Daniel Tomé, Cécile Bos, Paul J. Moughan, Amélie Deglaire
Rok vydání: 2009
Předmět:
Zdroj: British Journal of Nutrition. 102:1752-1759
ISSN: 1475-2662
0007-1145
Popis: The suitability of the pig as an animal model for predicting protein digestibility in man was evaluated. Healthy adult human subjects (mean body weight 67 kg;n11) and growing pigs (mean body weight 40 kg;n15) were fed semi-synthetic mixed meals containing, as a sole source of N, casein (C), hydrolysed casein (HC) or rapeseed isolate (R). There was no prior adaptation to the test meal. Ileal digesta were sampled through a naso-ileal tube (human subjects) or a post-valve T-caecum cannula (pigs) after ingestion of a bolus meal. The protein sources were15N-labelled. Amino acid (AA) digestibilities were not determined for R. Ileal apparent N digestibility was markedly lower (14–16 %;P P P P>0·05) between the species (C, HC). Exceptions were for phenylalanine, tyrosine, lysine, histidine and aspartic acid for which digestibilities were lower (3 % on average;P r0·98 over 3 × 2 data;P = 0·11) and AA (r0·87 over 26 × 2 data;P
Databáze: OpenAIRE