Binding of hemin and Congo red by oral hemolytic spirochetes

Autor: A. Klitorinos, I. R. Siboo, E. C. S. Chan, D. Scott, R. Siboo
Rok vydání: 1993
Předmět:
Zdroj: Oral Microbiology and Immunology. 8:245-250
ISSN: 1399-302X
0902-0055
DOI: 10.1111/j.1399-302x.1993.tb00568.x
Popis: Colony-forming units or cells in suspension of oral anaerobic spirochetes (Treponema denticola, Treponema vincentii and Treponema socranskii) bind hemin and Congo red. Hemin or Congo red binds to a hydrophobic polypeptide receptor that is located in the outer membrane of the bacterial cells and it has a relative molecular mass of 47 kDa. These oral spirochetes also lyse sheep erythrocytes to produce beta-hemolytic zones around colony-forming units. The oral spirochetes may acquire iron for growth when they lyse erythrocytes and bind heme from which they may sequester and transport iron into the cells.
Databáze: OpenAIRE