Binding of hemin and Congo red by oral hemolytic spirochetes
Autor: | A. Klitorinos, I. R. Siboo, E. C. S. Chan, D. Scott, R. Siboo |
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Rok vydání: | 1993 |
Předmět: |
Microbiology (medical)
Immunology Treponema vincentii Siderophores Receptors Cell Surface Hydrophobia Hemolysis Microbiology chemistry.chemical_compound medicine Treponema cvg General Dentistry Heme Mouth Binding Sites biology cvg.computer_videogame Congo Red Treponema denticola medicine.disease biology.organism_classification Congo red stomatognathic diseases chemistry Hemin Bacterial outer membrane Bacterial Outer Membrane Proteins |
Zdroj: | Oral Microbiology and Immunology. 8:245-250 |
ISSN: | 1399-302X 0902-0055 |
DOI: | 10.1111/j.1399-302x.1993.tb00568.x |
Popis: | Colony-forming units or cells in suspension of oral anaerobic spirochetes (Treponema denticola, Treponema vincentii and Treponema socranskii) bind hemin and Congo red. Hemin or Congo red binds to a hydrophobic polypeptide receptor that is located in the outer membrane of the bacterial cells and it has a relative molecular mass of 47 kDa. These oral spirochetes also lyse sheep erythrocytes to produce beta-hemolytic zones around colony-forming units. The oral spirochetes may acquire iron for growth when they lyse erythrocytes and bind heme from which they may sequester and transport iron into the cells. |
Databáze: | OpenAIRE |
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