Idiopathic Orbital Inflammation Associated With Necrotizing Scleritis and Temporal Bone Inflammation
| Autor: | H. Jane Kim, Larry Lustig, Ryan Basham, Sundeep K. Kasi, Robert C. Kersten, Aileen Sy, Emmett T. Cunningham |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty genetic structures Biopsy Azathioprine Diagnosis Differential Lesion Young Adult 03 medical and health sciences 0302 clinical medicine Ptosis Prednisone Orbital Pseudotumor Temporal bone medicine Humans Osteitis medicine.diagnostic_test business.industry Temporal Bone General Medicine medicine.disease eye diseases Ophthalmology 030220 oncology & carcinogenesis 030221 ophthalmology & optometry Female Surgery Rituximab medicine.symptom Tomography X-Ray Computed business Scleritis Follow-Up Studies medicine.drug |
| Zdroj: | Ophthalmic Plastic & Reconstructive Surgery. 32:e77-e79 |
| ISSN: | 0740-9303 |
| DOI: | 10.1097/iop.0000000000000251 |
| Popis: | The authors present a case of aggressive idiopathic orbital inflammation producing necrotizing scleritis along with synchronous tumefactive fibroinflammatory lesion of the temporal bone. A young woman with no medical history presented with sectoral scleritis and mildly reduced vision. Response to initial treatment, which included topical and systemic corticosteroids, as well as systemic nonsteroidal anti-inflammatory drugs, was limited. Over the following months, signs of orbital inflammation developed, including ptosis, proptosis, and limited extraocular motility. MRI revealed both orbital and ipsilateral temporal bone masses. An orbital biopsy was performed revealing a mixed inflammatory infiltrate, whereas a biopsy of the temporal bone mass revealed a tumefactive fibroinflammatory lesion. Biopsy showed no histopathologic evidence of infection nor neoplasm. The patient eventually responded to treatment with systemic prednisone, azathioprine, and rituximab. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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