Six undescribed derivatives of stilbene isolated from Lindera reflexa Hemsl. and their anti-tumor and anti-inflammatory activities

Autor:	Yu-Hang Fu, Ya-Di Hou, Yi-Zhe Duan, Xiao-Ya Sun, suiqing chen
Rok vydání:	2022
Předmět:	Lipopolysaccharides Pharmacology Molecular Structure Interleukin-6 Anti-Inflammatory Agents Antineoplastic Agents General Medicine Lindera Mice RAW 264.7 Cells A549 Cells Stilbenes Drug Discovery Humans Animals
Zdroj:	Fitoterapia. 163:105331
ISSN:	0367-326X
DOI:	10.1016/j.fitote.2022.105331
Popis:	Six undescribed stilbene derivatives Reflexanbene DH (1-4, 6) and Reflexanbene J (5), as well as one known stilbene 3,5-dimethoxystilbene (7), were isolated from the dried roots of Lindera reflexa Hemsl. Their structures and absolute configurations were elucidated using spectroscopy and electronic circular dichroism (ECD) analysis. In cytotoxic assays, moderately inhibitory activities of Reflexanbene F (3) against MGC80-3 and A549 cell lines were observed, with IC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca39e4f0046f3241b27c2fb6cc40c5ce https://doi.org/10.1016/j.fitote.2022.105331 Zobrazit plný text záznamu Full Text from ScienceDirect