Comparison of tolerance and nutritional outcome between a peptide and a standard enteral formula in critically ill, hypoalbuminemic patients
| Autor: | Rex O. Brown, Kenneth A. Kudsk, Christine A. Mowatt-Larssen, Stacey L. Wojtysiak |
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| Rok vydání: | 1992 |
| Předmět: |
Oncotic pressure
Adult Diarrhea Male Resuscitation Nitrogen balance medicine.medical_specialty 030309 nutrition & dietetics Nitrogen Critical Illness Medicine (miscellaneous) Nutritional Status Enteral administration Gastroenterology 03 medical and health sciences 0302 clinical medicine Enteral Nutrition Internal medicine medicine Pressure Humans Prealbumin Hypoalbuminemia Prospective Studies Prospective cohort study Serum Albumin 0303 health sciences Nutrition and Dietetics business.industry Transferrin Middle Aged medicine.disease Surgery Parenteral nutrition Standard enteral formula 030211 gastroenterology & hepatology Female business Peptides |
| Zdroj: | JPEN. Journal of parenteral and enteral nutrition. 16(1) |
| ISSN: | 0148-6071 |
| Popis: | Dipeptides have been reported to be more efficiently absorbed from the gastrointestinal tract than free amino acids. The objective of this study was to compare prospectively a peptide enteral formula (PEF) with a standard enteral formula (SEF) for tolerance and nutritional outcome in acutely injured, hypoalbuminemic (less than 3.0 g/dL) patients who require enteral nutrition support. The prevalence of diarrhea and elevated gastric residuals was assessed daily. Prealbumin, transferrin, colloid oncotic pressure, Prognostic Nutritional Index, and nitrogen balance were measured on days 0, 5, and 10 of enteral nutrition support. Forty-one patients received 345 days of enteral nutrition support. Prevalences of diarrhea and elevated gastric residuals were similar between groups. Prealbumin increased and the Prognostic Nutritional Index decreased significantly from baseline at day 10 in both groups. Transferrin increased in both groups, but not significantly. Colloid oncotic pressure increased significantly from baseline at days 5 and 10 in the SEF group and day 10 in the PEF group. Nitrogen balance increased significantly from baseline at days 5 and 10 in each group. The only significant difference between groups was for nitrogen balance at day 10, which was higher in the SEF group. We conclude based upon our selected measurements of tolerance and nutritional outcome PEF seems to offer no advantage over SEF in acutely injured, hypoalbuminemic patients. |
| Databáze: | OpenAIRE |
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