| Zdroj: |
Proietti, M, Romiti, G F, Vitolo, M, Borgi, M, Rocco, A D, Farcomeni, A, Miyazawa, K, Healey, J S, Lane, D A, Boriani, G, Basili, S & Lip, G Y H 2022, ' Epidemiology of subclinical atrial fibrillation in patients with cardiac implantable electronic devices : A systematic review and meta-regression ', European Journal of Internal Medicine, vol. 103, pp. 84-94 . https://doi.org/10.1016/j.ejim.2022.06.023 |
| Popis: |
BACKGROUND: In recent years, attention to subclinical atrial fibrillation (SCAF), defined as the presence of atrial high-rate episodes (AHREs), in patients with cardiac implantable electronic devices (CIEDs), has gained much interest as a determinant of clinical AF and stroke risk. We aim to perform a systematic review and meta-regression of the available scientific evidence regarding the epidemiology of SCAF in patients receiving CIEDs.METHODS: PubMed and EMBASE were searched for all studies documenting the prevalence of AHREs in patients (n=100 or more, RESULTS: Among the 2614 results initially retrieved, 54 studies were included, with a total of 72,784 patients. Meta-analysis of included studies showed a pooled prevalence of SCAF of 28.1% (95%CI: 24.3-32.1%), with high heterogeneity between studies (I 2=98%). A multivariable meta-regression was able to explain significant proportion of heterogeneity (R 2=61.9%, pCONCLUSIONS: In this systematic review and meta-regression analysis, SCAF was frequent among CIED recipients and was non-linearly associated with age and follow-up time. Older age, higher thromboembolic risk, and several cardiovascular comorbidities were associated with presence of SCAF. |
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