Recurrent life-threatening ventricular dysrhythmias associated with acute hydrofluoric acid ingestion: Observations in one case and implications for mechanism of toxicity
| Autor: | Wilfredo Rivera, Larissa I. Velez, Kathleen A. Delaney, Fernando L. Benitez, Rais Vohra |
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| Rok vydání: | 2008 |
| Předmět: |
Tachycardia
Hyperkalemia Heart disease Electric Countershock Toxicology Hydrofluoric Acid Calcium Chloride Electrocardiography chemistry.chemical_compound Hydrofluoric acid Oral administration medicine Humans Ingestion Magnesium Aged 80 and over Hypocalcemia business.industry Metabolic disorder Lidocaine food and beverages General Medicine medicine.disease chemistry Anesthesia Ventricular Fibrillation Toxicity Tachycardia Ventricular Female medicine.symptom Emergency Service Hospital business |
| Zdroj: | Clinical Toxicology. 46:79-84 |
| ISSN: | 1556-9519 1556-3650 |
| Popis: | Hydrofluoric acid (HF) is a weak inorganic acid used for etching and as rust remover. Systemic toxicity is manifested as ventricular dysrhythmias. The mechanisms for these dysrhythmias are not well elucidated.An 82-year-old woman ingested 8 ounces of 7% HF. Shortly after emergency department (ED) arrival, she became pulseless, developing recurrent ventricular dysrhythmias. She was defibrillated 17 times and received several doses of calcium, magnesium, and lidocaine. After three hours, she returned to sustained NSR. She was discharged home after four days.The electrocardiographic findings in this patient demonstrate hypocalcemia, which has been implicated as the culprit in HF-induced arrhythmias. However, despite correction of the hypocalcemia, the ventricular arrhythmias persisted. The proposed mechanisms of systemic HF toxicity and the relevant literature are discussed.Ventricular dysrhythmias due to HF toxicity seem to be independent of either hypocalcemia or hyperkalemia. Systemic toxicity after ingestions may be delayed and precipitous. |
| Databáze: | OpenAIRE |
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