Multilocular cystic renal cell carcinoma: comparison of imaging and pathologic findings
| Autor: | Jonathan Melamed, Nicole Hindman, Andrew B. Rosenkrantz, Stephanie Lee-Felker, Morton A. Bosniak |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Gadolinium DTPA Male medicine.medical_specialty Pathology Iohexol Contrast Media Diagnosis Differential Meglumine Fibrosis Carcinoma Organometallic Compounds Medicine Humans Radiology Nuclear Medicine and imaging Cyst Carcinoma Renal Cell Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Multilocular Cystic Renal Cell Carcinoma Kidney Diseases Cystic Middle Aged medicine.disease Magnetic Resonance Imaging Kidney Neoplasms Female Radiology Differential diagnosis business Tomography X-Ray Computed medicine.drug |
| Zdroj: | AJR. American journal of roentgenology. 198(1) |
| ISSN: | 1546-3141 |
| Popis: | The purpose of this study was to retrospectively correlate the imaging and pathologic features of multilocular cystic renal cell carcinoma (RCC), a low-grade neoplasm that has an excellent prognosis.Institutional databases were searched for the period between 2001 and 2010 to identify cases of resected renal tumors that had been evaluated with CT or MRI and been analyzed by a uropathologist to confirm the histologic diagnosis of multilocular cystic RCC. The images (nine CT, 14 MRI) were reviewed, and a Bosniak cyst category was assigned.Of 23 confirmed cases of multilocular cystic RCC, imaging revealed seven lesions were Bosniak category IIF, 13 were category III, and three were category IV. Pathologic examination of the category IIF lesions revealed 99% fluid, 0.001-1% clear cells lining the septum, and 0% fibrosis. The category III lesions were 98-99% fluid, 1-2% clear cells, and 0% fibrosis. The category IV lesions were 20-40% fluid, 1-5% clear cells, and 60-80% fibrosis. The patient demographics were similar across groups. Clinical follow-up showed no evidence of recurrent or metastatic disease.Multilocular cystic RCC is a rare cystic lesion of the kidney that is low risk to the patient and benign in behavior. It has a variable imaging pattern, the Bosniak category ranging from IIF to IV. As multilocular cystic RCC lesions increase in complexity on images (higher Bosniak category), there is a corresponding increase in the volume of malignant cells lining the tumor and an increase in the presence of vascularized fibrous tissue. Regardless of the imaging appearance, the behavior of these tumors was benign in this study. Clinicians and radiologists should be aware that when this carcinoma is reported to occur, the patient has an excellent prognosis. |
| Databáze: | OpenAIRE |
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