[Prevalence of SARS-CoV-2 coronavirus infection in patients and professional staff at a medium or long-stay hospital in Spain]

Autor: Luis Antonio Moreno Borraz, María Carmen Espinosa Val, Alejandro Sastre Heres, Rosa Lou Lou, Adriana Narvión Carriquiri, Javier Pérez Sans, Concepción Ortíz Domingo, Juan Carlos Gil Acebes, Evelyn Florentín Ostáriz, Marta Luzón Alonso, Mercedes Giménez López, Rosa Blanca Zabala Lahoz, Francisco Amorós de la Nieta, Consuelo López Santed, Patricia Carrera Lasfuentes, Fernando Arto Maza, Marta Barea Gil, Francisco Díaz Mora, Irene Aznar Vázquez, Belén Moragrega Cardona, Yolanda Rubio Morilla, Emilio González Pérez, Ana Coarasa Lirón de Robles, María Pilar Serrano Herrero, Ángel Luis García Forcada, José Luis Bonafonte Marteles, Ana Rosa Molina Morales, Raquel González Tejedor, María Mar Fernández Adarve, Mercedes García Mena, Raquel Sisas Rubio, Sara Parrilla Binué, Carmen Vicente Gaspar, Silvia Fernández Doblado
Rok vydání: 2020
Předmět:
Zdroj: Revista Española de Geriatría y Gerontología
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Revista Espanola De Geriatria Y Gerontologia
ISSN: 1578-1747
Popis: Background and goals: The aim of the study is to know the prevalence of SARS-CoV-2 infection in patients and professional staff of a medium or long-stay hospital during the peak period of the pandemic in Spain, spring 2020. Material and methods: At the end of February 2020, we developed at the hospital a strategy to diagnose the SARS-CoV-2 infection consisting of complementing the realization of PCR tests at real time with a quick technique of lateral flow immunochromatography to detect IgG and IgM antibodies against the virus. We also developed a protocol to realize those diagnostic tests and considered an infection (current or past) a positive result in any of the above tests. We included 524 participants in the study (230 patients and 294 hospital staff), and divided them into hospital patients and Hemodialysis outpatients. Furthermore, we divided the hospital staff into healthcare and non-healthcare staff. The documented period was from March, 20th to April, 21st, 2020. Results: 26 out of 230 patients tested positive in any of the diagnostic techniques (PCR, antibodies IgG, IgM) with a 11.30% prevalence. According to patients groups, we got a 14.38% prevalence in hospital patients vs. 5.95% in outpatients, with a significantly higher risk in admitted patients after adjustment for age and gender (OR=3, 309, 95%CI: 1, 154-9, 495). 24 out of 294 hospital staff tested positive in any of the diagnostic techniques, with a 8.16% prevalence. According to the groups, we got a 8.91% prevalence in healthcare staff vs. 4.26% in non-healthcare staff. Thus, we do not see any statistically significant differences between hospital staff and patients as far as prevalence is concerned (P=0, 391), (OR=2, 200, 95%CI: 0, 500-9, 689). Conclusions: The result of the study was a quite low prevalence rate of SARS-CoV-2 infection, in both patients and hospital staff, being the hospital patients’ prevalence rate higher than the outpatients’, and the healthcare staff higher than the non-healthcare''s. Combining PCR tests (gold standard) with antibodies tests proved useful as a diagnostic strategy.
Databáze: OpenAIRE
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