The effect of heart rate, acetylcholine, and vagal stimulation on antegrade and retrograde His-Purkinje conduction in the intact heart
| Autor: | Masood Akhtar, Anthony N. Damato, P.Jacob Varghese, Sun H. Lau, Gustavus A. Bobb |
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| Rok vydání: | 1973 |
| Předmět: |
Pacemaker
Artificial medicine.medical_specialty Time Factors Vagal stimulation Stimulation Electrocardiography Dogs Heart Conduction System Heart Rate Internal medicine Heart rate medicine Animals Pentobarbital His-Purkinje conduction medicine.diagnostic_test business.industry Heart Vagus Nerve Acetylcholine Electric Stimulation Stimulation Chemical Electrodes Implanted Cardiovascular physiology medicine.anatomical_structure Ventricle Anesthesia Anesthesia Intravenous Cardiology Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | American Heart Journal. 86:203-210 |
| ISSN: | 0002-8703 |
| DOI: | 10.1016/0002-8703(73)90245-7 |
| Popis: | In ten dogs the effects of acetylcholine, graded vagal stimulation, and heart rate on both antegrade and retrograde His-Purkinje conduction were evaluated. His bundle pacing was used to obtain the antegrade His-Purkinje conduction time and pacing the ventricle and recording the retrograde His bundle electrogram gave the retrograde His-Purkinje conduction time. Acetylcholine and vagal stimulation sufficient to produce cardiac arrest had no effect on antegrade and retrograde His-Purkinje conduction. Similarly, pacing at cycle lenghts varying from 400 to 200 msec. had no effect on antegrade or retrograde conduction time. However, when the cycle length of ventricular pacing was decreased to less than 200 msec. various degrees of retrograde His-Purkinje conduction delay and block developed. |
| Databáze: | OpenAIRE |
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