Eyelid healing after carbon dioxide laser skin resurfacing: histological analysis
| Autor: | Alan H. Friedman, Murray A. Meltzer, Geva E. Mannor, Robert G. Phelps |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Blepharoplasty
Male Eyelid Skin medicine.medical_specialty medicine.medical_treatment Dermatologic Surgical Procedures Dermis Ophthalmology Medicine Humans Aged Skin Aged 80 and over Wound Healing business.industry Eyelids Anatomy Carbon dioxide laser Middle Aged Plastic surgery medicine.anatomical_structure Rhytidoplasty Female sense organs Epidermis Eyelid Laser Therapy business Elastic fiber |
| Zdroj: | Archives of ophthalmology (Chicago, Ill. : 1960). 117(7) |
| ISSN: | 0003-9950 |
| Popis: | Objective To clarify in vivo healing of eyelid skin after carbon dioxide (CO2) laser resurfacing. Design Patients requesting upper eyelid blepharoplasty consented to undergo previous CO2laser skin resurfacing of the upper eyelid skin segments to be excised at various time intervals. After blepharoplasty, the skin specimens were analyzed histopathologically by 2 masked pathologists. Patients Eight patients with Fitzpatrick skin types I and II. Intervention Upper eyelid CO2laser resurfacing 1,2, 4, or 12 weeks before planned upper eyelid blepharoplasty. Main Outcome Measures Epidermis: thickness, polarity, contour, and constituents. Dermis: repair zone thickness, vascular and inflammatory pattern, collagen deposition, and elastic fiber changes. Results The epidermis regenerated within 7 to 10 days. By 3 months, the epidermis revealed flattening of the rete peg pattern with restoration of polarity, keratinocytes, and melanocytes. The 3-month dermis demonstrated a fibrotic repair zone (500-700 µm), new elastic fibers, and telangiectatic capillaries. Conclusions Eyelids heal similarly to other skin regions treated by CO2laser resurfacing. This cutaneous healing is analogous to that previously reported with use of chemical peels. Histological changes may explain the skin smoothing and wrinkle reduction seen clinically. |
| Databáze: | OpenAIRE |
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