Endobronchial tuberculosis presenting as asthma
Autor: | Ernest L. York, Ewa Nobert, Dave Williams, Brian J. Sproule |
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Rok vydání: | 1988 |
Předmět: |
Pulmonary and Respiratory Medicine
Adult Male medicine.medical_specialty Allergy Tuberculosis Antitubercular Agents Disease Critical Care and Intensive Care Medicine Mycobacterium tuberculosis Pharmacotherapy Bronchoscopy Internal medicine medicine Humans Tuberculoma Child Tuberculosis Pulmonary Asthma medicine.diagnostic_test biology business.industry Respiratory disease Infant medicine.disease biology.organism_classification Immunology Female Cardiology and Cardiovascular Medicine business |
Zdroj: | Chest. 93(4) |
ISSN: | 0012-3692 |
Popis: | Clinical deterioration with features suggestive of asthma was seen in three patients following two to six months of drug therapy of primary tuberculosis. There was a poor clinical response to administered bronchodilators. Bronchoscopy in all three revealed culture-negative mycobacterial caseating granulomas. Corticosteroid therapy resulted in good clinical response, with resolution of the asthmatic symptoms and improvement in the expiratory flow rates. In our opinion these patients are clinically compatible with a hypersensitivity response to mycobacteria following antituberculosis therapy and release of tuberculosis antigens. Corticosteroid therapy is appropriate in this form of tuberculous disease. |
Databáze: | OpenAIRE |
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