Fatty Acid Composition of the Erythrocyte Membranes Varies between Early-Term, Full-Term, and Late-Term Infants in Japan
| Autor: | Chieko Kogomori, Yohei Kitamura, Seigo Shiga, Iwao Maekawa, Takashi Shimizu, Hirokazu Hamano |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Cord Docosahexaenoic Acids Pregnancy Trimester Third Medicine (miscellaneous) Physiology Gestational Age Cohort Studies 03 medical and health sciences chemistry.chemical_compound Japan Pregnancy Fatty Acids Omega-3 Medicine Humans Prospective Studies Full Term chemistry.chemical_classification 030109 nutrition & dietetics Nutrition and Dietetics Arachidonic Acid business.industry Erythrocyte Membrane Fatty Acids Infant Newborn Fetal Blood Term (time) Diet Membrane chemistry Docosahexaenoic acid Arachidonic acid Female business Infant Premature Cohort study Polyunsaturated fatty acid |
| Zdroj: | Annals of nutritionmetabolism. 73(4) |
| ISSN: | 1421-9697 |
| Popis: | Background: Term infants can be categorized into 3 sub-groups: early term (37w0d to 38w6d), full term (39w0d to 40w6d), and late term (41w0d and beyond). However, the fatty acid composition among the 3 groups of term infants has not been investigated. The association between fatty acid composition and gestational period of term infants in Japan is unclear. Methods: We assessed the fatty acid composition of maternal erythrocyte membranes in the third trimester and of cord erythrocyte membranes at birth in 212 healthy term Japanese infants using data from a prospective hospital-based cohort study. Results: In maternal erythrocyte membranes, docosahexaenoic acid (DHA) levels and omega-3 index were significantly higher in the late-term group than in the early-term group. In cord erythrocyte membranes, DHA levels were not significantly different between the 3 groups; late-term infants showed significantly higher DHA/arachidonic acid (ARA) and lower 20: 3n-6 and ARA levels compared to early-term infants. Gestational period positively correlated with the DHA status in maternal and cord erythrocyte membranes. Conclusions: Fatty acid composition in maternal and cord erythrocyte membranes varies between early-, full-, and late-term infants, and the greater gestational period may contribute to the relatively high n-3 polyunsaturated fatty acids status in term infants. Furthermore, maternal DHA status in the third semester directly correlates with gestational period in pregnant Japanese women. |
| Databáze: | OpenAIRE |
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