Surgical Site Infections in patients undergoing major oncological surgery during the COVID‐19 paNdemic (SCION): A propensity‐matched analysis
| Autor: | Vikram Chaudhari, Shalaka Joshi, Gouri Pantvaidya, Shraddha Patkar, Devayani Niyogi, Rajendra A Badwe, Gagan Prakash, Preeti Vijaykumaran, Ajay Puri, Pabashi Poddar, Poonam Joshi, Vikas Singh, Sadhana Kannan, Deepa Nair, Prakash Nayak, Saumya Mathews, Richa Vaish, Ashwin Desouza, C S Pramesh |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty media_common.quotation_subject Disease Hygiene Risk Factors Internal medicine Neoplasms Odds Ratio Medicine Humans Surgical Wound Infection Stage (cooking) Propensity Score Research Articles media_common Retrospective Studies Infection Control propensity score matching business.industry Incidence (epidemiology) Incidence COVID-19 Surgical wound COVID‐19 pandemic General Medicine Odds ratio surgical site infection Middle Aged Confidence interval Logistic Models Oncology Elective Surgical Procedures Propensity score matching Surgery Female business Algorithms Research Article oncologic surgery |
| Zdroj: | Journal of Surgical Oncology |
| ISSN: | 1096-9098 0022-4790 |
| Popis: | Background and Objectives There are reports of outcomes of elective major cancer surgery during the COVID‐19 pandemic. We evaluated if reinforcement of hand hygiene, universal masking, and distancing as a part of pandemic precautions led to a decrease in the incidence of surgical site infections (SSIs) in major oncologic resections. Methods Propensity score matching using the nearest neighbor algorithm was performed on 3123 patients over seven covariates (age, comorbidities, surgery duration, prior treatment, disease stage, reconstruction, and surgical wound type) yielding 2614 matched (pre‐COVID 1612 and COVID 1002) patients. Conditional logistic regression was used to identify if SSI incidence was lower amongst patients operated during the pandemic. Results There was a 4.2% (p = 0.006) decrease in SSI in patients operated during the pandemic. On multivariate regression, surgery during the COVID‐19 period (odds ratio [OR] = 0.77; 95% confidence interval [CI] = 0.61–0.98; p = 0.03), prior chemoradiation (OR = 2.46; CI = 1.45–4.17; p 4 h (OR = 2.17; 95%CI = 1.55–3.05; p |
| Databáze: | OpenAIRE |
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