Cost-Consequences Analysis of Increased Utilization of Triple-Chamber-Bag Parenteral Nutrition in Preterm Neonates in Seven European Countries
| Autor: | Alexander Kriz, Antony Wright, Mattias Paulsson, Stephen Tomlin, Venetia Simchowitz, Julian Shepelev, Thibault Senterre |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Budgets
Male medicine.medical_specialty Full-time Cost consequences Drug Compounding compounding errors preterm neonates Pharmacy lcsh:TX341-641 parenteral nutrition Pediatrics Article 03 medical and health sciences 0302 clinical medicine Cost Savings Bloodstream infection Health care medicine Medical Staff Hospital Humans 030212 general & internal medicine Economics Hospital Nutrition and Dietetics Medical Errors business.industry ready-to-use three-chamber-bags Infant Newborn Pediatrik Patient Acceptance of Health Care Cost savings Europe Parenteral nutrition Emergency medicine Costs and Cost Analysis cost-consequence analysis Staff time Health Resources 030211 gastroenterology & hepatology Female Safety business lcsh:Nutrition. Foods and food supply Infant Premature Food Science |
| Zdroj: | Nutrients Volume 12 Issue 9 Nutrients, Vol 12, Iss 2531, p 2531 (2020) |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu12092531 |
| Popis: | The safety of parenteral nutrition (PN) remains a concern in preterm neonates, impacting clinical outcomes and health-care-resource use and costs. This cost-consequence analysis assessed national-level impacts of a 10-percentage point increase in use of industry-prepared three-chamber bags (3CBs) on clinical outcomes, healthcare resources, and hospital budgets across seven European countries. A ten-percentage-point 3CB use-increase model was developed for Belgium, France, Germany, Italy, Portugal, Spain, and the UK. The cost-consequence analysis estimated the impact on compounding error harm and bloodstream infection (BSI) rates, staff time, and annual hospital budget. Of 265,000 (52%) preterm neonates, 133,000 (52%) were estimated to require PN. Baseline compounding methods were estimated as 43% pharmacy manual, 16% pharmacy automated, 22% ward, 9% outsourced, 3% industry provided non-3CBs, and 7% 3CBs. A modeled increased 3CB use would change these values to 39%, 15%, 18%, 9%, 3%, and 17%, respectively. Modeled consequences included &minus 11.6% for harm due to compounding errors and &minus 2.7% for BSIs. Labor time saved would equate to 41 specialized nurses, 29 senior pharmacists, 26 pharmacy assistants, and 22 senior pediatricians working full time. Budget impact would be a &euro 8,960,601 (3.4%) fall from &euro 260,329,814 to &euro 251,369,212. Even a small increase in the use of 3CBs in preterm neonates could substantially improve neonatal clinical outcomes, and provide notable resource and cost savings to hospitals. |
| Databáze: | OpenAIRE |
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