APOE-isoform dependent effects on subretinal inflammation and cardinal features of AMD

Autor:	Guillonneau, Xavier, Levy, O., Lavalette, S., Sahel, J.-A., Sullivan, P., Sennlaub, F.
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	genetic structures ddc: 610 lipids (amino acids peptides and proteins) sense organs 610 Medical sciences Medicine eye diseases
Zdroj:	VI. International Symposium on AMD-Age-Related Macular Degeneration-Emerging Concepts-Exploring known and Identifying new Pathways; 20150911-20150912; Baden-Baden; DOC15amd10 /20151001/
Popis:	Background: It is well established that the APOE2-allele increases and the APOE4-allele reduces, the risk to develop age related macular degeneration (AMD) compared to the most common APOE3-allele. How the APOE isoforms affect AMD pathogenesis is unknown. We previously demonstrated that APOE promotes[for full text, please go to the a.m. URL] VI. International Symposium on AMD – Age-Related Macular Degeneration – Emerging Concepts – Exploring known and Identifying new Pathways
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ef4781a4e7b0283c1e2556e7756a03 http://www.egms.de/en/meetings/amd2015/15amd10.shtml Zobrazit plný text záznamu