Regulation of liver glucose-6-P dehydrogenase levels in female rats
| Autor: | Darold Holten, Lisa Kibbee Reichert, Jesus R. Carlos, Roderick Nakayama |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Physiology Dehydrogenase Biology Glucosephosphate Dehydrogenase Biochemistry Rats Sprague-Dawley chemistry.chemical_compound Biosynthesis Glucose dehydrogenase hemic and lymphatic diseases Internal medicine parasitic diseases Gene expression medicine Animals Homeostasis RNA Messenger Molecular Biology chemistry.chemical_classification Messenger RNA Sex Characteristics nutritional and metabolic diseases General Medicine Metabolism Fasting Diet Rats Sexual dimorphism Kinetics Endocrinology Enzyme chemistry Liver Female |
| Zdroj: | Comparative biochemistry and physiology. B, Comparative biochemistry. 104(1) |
| ISSN: | 0305-0491 |
| Popis: | 1. 1. Gender differences in the dietary regulation of rat liver glucose-6-P dehydrogenase activity, synthesis and mRNA levels were examined. 2. 2. As expected, in normal rats fed a standard chow diet, females have higher G6PD activity than males because they have more G6PD mRNA and therefore a higher rate of G6PD synthesis. 3. 3. In contrast, the decreased dietary induction in female rats is due to a more rapid rate of G6PD degradation rather than a decrease in G6PD mRNA or synthesis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|