Relationship between late embryonic mortality and the increase in plasma advanced oxidised protein products (AOPP) in dairy cows
| Autor: | Olimpia Barbato, Laura Da Dalt, Pietro Celi, Gianfranco Gabai, Mariacristina Merlo, Annalisa Stefani |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Glycation End Products
Advanced inflammation protein oxidation Cattle Diseases Gestational Age Reproductive technology Biology Protein oxidation Andrology chemistry.chemical_compound Endocrinology Pregnancy Lactation Genetics medicine Animals protein oxidation Molecular Biology Insemination Artificial Dairy cows Embryo loss Advanced Oxidized Protein Products Blood Proteins Embryo Mammalian Malondialdehyde medicine.disease Blood proteins Dairying medicine.anatomical_structure Reproductive Medicine chemistry Advanced oxidation protein products inflammation Immunology Pregnancy Animal Cattle Female Animal Science and Zoology Oxidation-Reduction Spermatogenesis Developmental Biology Biotechnology |
| Popis: | The involvement of protein oxidation in embryonic mortality (EM) has been poorly investigated in cows. Advanced oxidation protein products (AOPP) are markers of protein oxidation generated by activated neutrophils and involved in inflammation. The aim of this work was to study AOPP in cow plasma and their relationship with late EM. The outcomes of 158 artificial inseminations (AI) were examined in 72 cows, which were classified ex post on the basis of blood progesterone and pregnancy-associated glycoprotein concentrations and clinical confirmation of pregnancy into the following categories: (1) positive (AI+, resulted in pregnancy, n = 58), (2) negative (AI–, did not result in pregnancy, n = 86) and (3) embryonic mortality (EM, n = 14). Plasma protein fractions, malondialdehyde (MDA), total glutathione and AOPP were measured at AI (Day 0) and on Days 15, 28, 35, 45 and 60. MDA was significantly higher in EM than AI+ and AI– animals on Day 45, and than AI+ animals on Day 60 (P |
| Databáze: | OpenAIRE |
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