Epidemiological study of congenital heart diseases in dogs: Prevalence, popularity, and volatility throughout twenty years of clinical practice

Autor: Michele Polli, Danitza Pradelli, Rita Rizzi, Mara Bagardi, Claudio Bussadori, Paola Brambilla, Melissa Papa
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Heart Septal Defects
Ventricular
Male
Pediatrics
Breeding
Pathology and Laboratory Medicine
Heart Septal Defects
Atrial
0403 veterinary science
Epidemiology
Medicine and Health Sciences
Morphogenesis
Odds Ratio
Prevalence
Medicine
Dog Diseases
Stenosis
Mammals
0303 health sciences
education.field_of_study
Multidisciplinary
biology
Pets and Companion Animals
Eukaryota
Heart
04 agricultural and veterinary sciences
Congenital Heart Defects
Veterinary Diagnostics
Breed
Pulmonary Valve Stenosis
Vertebrates
Female
Anatomy
Research Article
Veterinary Medicine
Heart Defects
Congenital
medicine.medical_specialty
Dysplasia
040301 veterinary sciences
Pulmonic stenosis
Cardiac Ventricles
Science
Animal Types
biology.animal_breed
Population
Cardiology
French bulldog
03 medical and health sciences
Signs and Symptoms
Dogs
Diagnostic Medicine
Congenital Disorders
Animals
Birth Defects
education
030304 developmental biology
Retrospective Studies
Cavalier King Charles spaniel
business.industry
Organisms
Biology and Life Sciences
Logistic Models
Amniotes
Ventricular Septal Defects
Cardiovascular Anatomy
Veterinary Science
business
Purebred
Zoology
Rottweiler
Developmental Biology
Zdroj: PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0230160 (2020)
ISSN: 1932-6203
Popis: The epidemiology of Congenital Heart Diseases (CHDs) has changed over the past twenty years. This study aimed to evaluate the prevalence of CHDs in the population of dogs recruited in a single referral center (RC); compare the epidemiological features of CHDs in screened breeds (Boxers) versus non-screened (French and English Bulldogs, German Shepherds); investigate the association of breeds with the prevalence of CHDs; determine the popularity and volatility of breeds over a 20-year period; analysed the trends of the most popular breeds in the overall population of new-born dogs registered in the Italian Kennel Club (IKC) from 1st January 1997 to 31st December 2017. The RC's cardiological database was analysed, and 1,779 clinical records were included in a retrospective observation study. Descriptive statistics and frequencies regarding the most representative breeds and CHDs were generated. A logistic regression model was used to analyse the trends of the most common CHDs found in single and in cluster of breeds. The relationship between breed popularity and presence of CHDs was studied. The most common CHDs were Pulmonic Stenosis, Patent Ductus Arteriosus, Subaortic Stenosis, Ventricular Septal Defect, Aortic Stenosis, Tricuspid Dysplasia, Atrial Septal Defect, Double Chamber Right Ventricle, Mitral Dysplasia, and others less frequent. The most represented pure breeds were Boxer, German Shepherd, French Bulldog, English Bulldog, Maltese, Newfoundland, Rottweiler, Golden Retriever, Chihuahua, and others in lower percentage. Chihuahuas, American Staffordshire Terriers, Border Collies, French Bulldogs, and Cavalier King Charles Spaniel were the most appreciated all of which showed a high value of volatility. This study found evidence for the value of the screening program implemented in Boxers; fashions and trends influence dog owners' choices more than the worries of health problems in a breed. Effective breeding programs are needed in order to control the diffusion of CHDs without impoverishing the genetic pool.
Databáze: OpenAIRE
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