Diagnosis of Coliform Infection in Acutely Dysuric Women

Autor: George W. Counts, Marvin Turck, Stephen D Fihn, Walter E. Stamm, Katherine Running, King K. Holmes
Rok vydání: 1982
Předmět:
Zdroj: New England Journal of Medicine. 307:463-468
ISSN: 1533-4406
0028-4793
DOI: 10.1056/nejm198208193070802
Popis: We reevaluated conventional criteria for diagnosing coliform infection of the lower urinary tract in symptomatic women by obtaining cultures of the urethra, vagina, midstream urine, and bladder urine. The traditional diagnostic criterion, greater than or equal to 10(5) bacteria per milliliter of midstream urine, identified only 51 per cent of women whose bladder urine contained coliformis. We found the best diagnostic criterion to be greater than or equal to 10(2) bacteria per milliliter (sensitivity, 0.95; specificity, 0.85). Although isolation of less than 10(5) coliforms per milliliter of midstream urine has had a low predictive value of previous studies of asymptomatic women, the predictive value of the criterion of greater than or equal to 10(2) per milliliter was high (0.88) among symptomatic women the prevalence of coliform infection exceeded 50 per cent. In view of these findings, clinicians and microbiologists should alter their approach to the diagnosis and treatment of women with acute symptomatic coliform infection of the lower urinary tract.
Databáze: OpenAIRE