The antibacterial activity of Libyan honey against gram negative bacilli: Potential treatment agent for infectious diseases?
| Autor: | Basma Doro, Nouha Elmarbet, Sarah Fouch, Mohamed Elemam, Bashir A. Lwaleed, Mahmoud Ben Shaban |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
food.ingredient gram negative Pharmacy Bacterial growth medicine.disease_cause 01 natural sciences 03 medical and health sciences 0302 clinical medicine food Antibiotic resistance antibacterial activity Esherichia coli medicine Agar Food science Yersinia enterocolitica Proteus mirabilis Escherichia coli Libyan honey biology Chemistry digestive oral and skin physiology food and beverages General Medicine Antimicrobial biology.organism_classification 010602 entomology 030220 oncology & carcinogenesis Antibacterial activity |
| Zdroj: | Elmarbet, N, Shaban, M, Doro, B, Lwaleed, B, Fouch, S & Elemam, M 2018, ' The antibacterial activity of Libyan honey against gram negative bacilli: potential treatment agent for infectious diseases? ' Journal of Advances in Medicine and Medical Research, vol. 25, no. 7, 39349 . https://doi.org/10.9734/JAMMR/2018/39349 |
| DOI: | 10.9734/JAMMR/2018/39349 |
| Popis: | Aims: Honey has is a rich source of many compounds that exhibit anti-microbial, anti-inflammatory and pro-angiogenic properties. The emergence of antibiotic resistance in a wide variety of bacterial pathogens has generated renewed interest in natural antimicrobials. The aim of the present study was to assess the antibacterial activity of Libyan honey in vitro.Methodology: The antibacterial activities of selected Libyan origin honey including Libyan Spring, AL-Sader, Thyme and Al-Hanone (at 25%, 50%, 75% and 100 % (w/v)) were tested against Yersinia enterocolitica, Escherichia coli and Proteus mirabilis using agar well-diffusion assay. The measurement of exponential bacterial growth curves was used to determine the effects on the microbial growth pattern spectrophotometrically at 600 nm. In addition, plate count methods were used to enumerate the effects of honey on the viable bacterial count.Results and Discussion: Honey progressively inhibited bacterial growth at higher concentrations. This effect was variable depending on the honey type. For example, Al Sader honey showed the highest inhibition zones 21.3 mm ±0.8 against P. mirabilis followed by Thyme (21 mm ±0.5) and spring (20 mm ±0.5). Al-Hanone honey only exhibited effects against E. coli (14 mm ±0.5 and 8 mm ±0.4 at 100% w/v and 75% w/v, respectively). The Al Sader, spring and Thyme honey significantly reduced the Yersinia enterocolitica bacteria growth curve (pConclusion: All honey tested showed inhibition of bacterial growth. Concentrated honeys were more effective against Yersinia enterocolitica, Escherichia coli and Proteus mirabilis. The efficacy of different types of honey was dependent on the honey concentration and origin. |
| Databáze: | OpenAIRE |
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