Clinical and radiographic predictors of the etiology of computed tomography-diagnosed intrathoracic lymphadenopathy in HIV-infected patients
| Autor: | Keith J. Edinburgh, Robert M. Jasmer, W. Richard Webb, Michael B. Gotway, Jennifer M. Creasman, Laurence Huang |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis Lung Neoplasms Opportunistic infection Radiography HIV Infections Pneumonia Bacterial Medicine Humans Pharmacology (medical) Lymphatic Diseases Sarcoma Kaposi Tuberculosis Pulmonary Lymphoma AIDS-Related Mycobacterium Infections AIDS-Related Opportunistic Infections business.industry Pneumonia Pneumocystis Bacterial pneumonia Middle Aged medicine.disease respiratory tract diseases Lymphoma Surgery Pneumonia Infectious Diseases Etiology Female Radiology Sarcoma business Tomography X-Ray Computed |
| Zdroj: | Journal of acquired immune deficiency syndromes (1999). 31(3) |
| ISSN: | 1525-4135 |
| Popis: | In HIV-infected patients with intrathoracic lymphadenopathy, it is not known whether clinical and radiographic findings are useful in predicting a specific diagnosis. We determined the etiology and predictors of the etiology of computed tomography (CT)-diagnosed intrathoracic lymphadenopathy in HIV-infected patients evaluated from June 1993 through April 1999. Multivariate analyses were performed to determine clinical and radiographic predictors of the three most common diagnoses. Of 318 patients, 110 (35%) had lymphadenopathy on chest CT. Among these 110 patients, tuberculosis/nontuberculous mycobacterial disease ( = 31), bacterial pneumonia ( = 26), and lymphoma ( = 21) were the most common diagnoses. Multivariate analysis identified cough and necrosis of lymph nodes on chest CT as independent predictors of tuberculosis/nontuberculous mycobacterial disease. African-American race, symptoms for 1 to 7 days, dyspnea, and presence of airways disease on chest CT were independent predictors of bacterial pneumonia; symptoms for >7 days, absence of cough, and absence of pulmonary nodules on CT independently predicted lymphoma. Intrathoracic lymphadenopathy is a frequent chest CT finding in HIV-infected patients. Opportunistic infections and lymphoma are the most common causes, and specific clinical and radiographic features can suggest these particular diagnoses. |
| Databáze: | OpenAIRE |
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