Congenital portosystemic shunts associated with liver tumours

Autor: L.F. Pupulim, Dominique Valla, Sylvain Terraz, Marie-Pierre Vullierme, Valérie Paradis, Valérie Vilgrain
Rok vydání: 2013
Předmět:
Adult
Male
medicine.medical_specialty
Adolescent
Adenoma
Vascular Malformations
complex mixtures
ddc:616.0757
Systemic circulation
Adenoma
Liver Cell
Young Adult
stomatognathic system
Focal Nodular Hyperplasia/complications/pathology
Vascular Malformations/complications/pathology
Biopsy
medicine
Humans
Radiology
Nuclear Medicine and imaging
Portal Vein/abnormalities/pathology
Liver Neoplasms/complications/pathology
Adenoma
Liver Cell/complications/pathology
Retrospective Studies
medicine.diagnostic_test
Portal Vein
business.industry
Liver Neoplasms
Biopsy
Needle
Focal nodular hyperplasia
Ultrasonography
Doppler
Retrospective cohort study
Magnetic resonance imaging
General Medicine
Liver tumours
Hepatocellular adenoma
medicine.disease
Magnetic Resonance Imaging
carbohydrates (lipids)
stomatognathic diseases
Focal Nodular Hyperplasia
Female
Radiology
Tomography
X-Ray Computed
business
Zdroj: Clinical Radiology, Vol. 68, No 7 (2013) pp. e362-9
ISSN: 0009-9260
DOI: 10.1016/j.crad.2013.01.024
Popis: Aim To evaluate the diagnosis and presentation of liver tumours in patients with congenital portosystemic shunts (CPS). Materials and methods Eight patients were diagnosed in Hopital Beaujon as having CPS. All patients underwent Doppler ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and histological examination of liver tumours. CPS were classified according to anatomy and the amount of portal flow deviated to the systemic circulation as: total, subtotal, or partial. Liver tumours were diagnosed by needle core biopsy ( n = 5) or surgery ( n = 3). Clinical follow-up was available in all patients but one (mean follow-up 36 months; range 1–5 years). Results Six patients had total CPS, one patient had a subtotal CPS, and the last had a partial CPS. All patients presented with multiple liver nodules (range four to >15). The tumours were characterized as focal nodular hyperplasia (FNH; n = 4), FNH with hepatocellular adenoma ( n = 2), and regenerative nodular hyperplasia ( n = 2). In four of seven patients (57%) that had follow-up, tumours showed enlargement or new lesions appeared. Conclusion In this series of CPS patients, tumours were all benign, multiple, and of hepatocellular origin, and different tumours were present simultaneously in two patients. Tumour enlargement or new nodules were common during follow-up.
Databáze: OpenAIRE
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