Soluble milk proteins improve muscle mass recovery after immobilization-induced muscle atrophy in old rats but do not improve muscle functional property restoration

Autor: Vincent Martin, Julien Verney, Monique Etienne, Lydie Combaret, Pascal Sirvent, Vivien Chavanelle, Dominique Dardevet, M. Bargetto, Elodie Chaplais, Nathalie Boisseau, Sébastien Ratel, Christelle Guillet, Cécile Bonhomme, P. Le Ruyet
Přispěvatelé: Laboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne (UCA)-UFR Sciences et Techniques des Activités Physiques et Sportives - Clermont-Auvergne (UFR STAPS - UCA), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), LACTALIS RECHERCHE ET DEVELOPPEMENT (LACTALIS R&D), Groupe Lactalis, Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Laboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques - Clermont Auvergne (AME2P), Faculté des Sciences du SportFaculté des Sciences du Sport, UFR STAPS-Université Clermont Auvergne (UCA), Lactalis Nutrition Santé, Unité de Nutrition Humaine - Clermont Auvergne (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne (UCA), Clermont Université-Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Recherche Agronomique (INRA), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-UFR Sciences et Techniques des Activités Physiques et Sportives - Clermont-Auvergne (UFR STAPS - UCA), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-UFR Sciences et Techniques des Activités Physiques et Sportives - Clermont-Ferrand (UFR STAPS - UBP), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP), Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH Auvergne), Lactalis Nutrition Santé [Laval] (LNS), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Centre de Recherche en Nutrition Humaine Auvergne [CHU Clermont-Ferrand] (CRNH A), Direction de la recherche clinique et de l’innovation [CHU Clermont-Ferrand] (DRCI), CHU Clermont-Ferrand-CHU Clermont-Ferrand
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
Male
medicine.medical_specialty
Sarcopenia
[SDV]Life Sciences [q-bio]
Medicine (miscellaneous)
Oxidative phosphorylation
Hindlimb
Isometric exercise
03 medical and health sciences
Immobilization
Casein
Internal medicine
medicine
[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]
Animals
Longitudinal Studies
Muscle Strength
Rats
Wistar
Muscle
Skeletal
ComputingMilieux_MISCELLANEOUS
030109 nutrition & dietetics
Nutrition and Dietetics
business.industry
muscle function
[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology
[SDV.BA]Life Sciences [q-bio]/Animal biology
aging
Skeletal muscle
food and beverages
Anatomy
Longitudinal animal study
muscle mass recovery
medicine.disease
Milk Proteins
Muscle atrophy
Rats
Muscular Atrophy
030104 developmental biology
Endocrinology
medicine.anatomical_structure
Whey Proteins
Geriatrics and Gerontology
medicine.symptom
business
[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Zdroj: Journal of Nutrition, Health & Aging
Journal of Nutrition, Health & Aging, 2017, 21 (10), pp.1133-1141. ⟨10.1007/s12603-016-0855-2⟩
Journal of Nutrition, Health and Aging
Journal of Nutrition, Health and Aging, Springer Verlag (Germany), In press, ⟨10.1007/s12603-016-0855-2⟩
Journal of Nutrition, Health and Aging, Springer Verlag (Germany), 2017, 21 (10), pp.1133-1141. ⟨10.1007/s12603-016-0855-2⟩
ISSN: 1279-7707
1760-4788
Popis: International audience; Effect of 3 different dairy protein sources on the recovery of muscle function after limb immobilization in old rats.Longitudinal animal study.Institut National de la Recherche Agronomique (INRA). The study took part in a laboratory setting.Old rats were subjected to unilateral hindlimb immobilization for 8 days and then allowed to recover with 3 different dietary proteins: casein, soluble milk proteins or whey proteins for 49 days.Body weight, muscle mass, muscle fibre size, isometric, isokinetic torque, muscle fatigability and muscle oxidative status were measured before and at the end of the immobilization period and during the recovery period i.e 7, 21, 35 and 49 days post immobilization.In contrast to the casein diet, soluble milk proteins and whey proteins were efficient to favor muscle mass recovery after cast immobilization during aging. By contrast, none of the 3 diary proteins was able to improve muscle strength, power and fatigability showing a discrepancy between the recovery of muscle mass and function. However, the soluble milk proteins allowed a better oxidative capacity in skeletal muscle during the rehabilitation period.Whey proteins and soluble milk proteins improve muscle mass recovery after immobilization-induced muscle atrophy in old rats but do not allow muscle functional property restoration.
Databáze: OpenAIRE
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