Characterization and evolution of major histocompatibility complex class II genes in the aye-aye, Daubentonia madagascariensis
| Autor: | Yoshi Kawamoto, Taizo Shima, Hirohisa Hirai, Naoki Koyama, Gilbert Rakotoarisoa, Albert Randrianjafy, Roger Mora, Yasuhiro Go |
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| Rok vydání: | 2003 |
| Předmět: |
Population
Genes MHC Class II Molecular Sequence Data Lemur Major histocompatibility complex Evolution Molecular Species Specificity Phylogenetics biology.animal Genetic variation Madagascar Animals Cluster Analysis Allele education Phylogeny DNA Primers education.field_of_study biology Base Sequence Geography Aye-aye Genetic Variation Sequence Analysis DNA biology.organism_classification Strepsirhini Evolutionary biology Animal ecology biology.protein Animal Science and Zoology |
| Zdroj: | Primates; journal of primatology. 46(2) |
| ISSN: | 0032-8332 |
| Popis: | Major histocompatibility complex genes (Mhc-DQB and Mhc-DRB) were sequenced in seven aye-ayes (Daubentonia madagascariecsis), which is an endemic and endangered species in Madagascar. An aye-aye from a north-eastern population showed genetic relatedness to individuals of a north-western population and had a somewhat different repertoire from another north-eastern individual. These observations suggest that the extent of genetic variation in Mhc genes is not excessively small in the aye-aye in spite of recent rapid destruction of their habitat by human activities. In light of Mhc gene evolution, trans-species and allelic polymorphisms can be estimated to have been retained for more than 50 Ma (million years) based on the time scale of lemur evolution. |
| Databáze: | OpenAIRE |
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