Exophiala dermatitidis pneumonia with bronchiectasis required prolonged voriconazole treatment
| Autor: | Susumu Sakamoto, Ryo Sekiguchi, Naohisa Urabe, Masakazu Sasaki, Sakae Homma, Kazuma Kishi |
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| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Case Report Case Reports Gastroenterology non‐cystic fibrosis Diseases of the respiratory system 03 medical and health sciences 0302 clinical medicine Lower respiratory tract infection Internal medicine voriconazole medicine Voriconazole Bronchiectasis RC705-779 medicine.diagnostic_test biology business.industry Respiratory infection medicine.disease biology.organism_classification respiratory tract diseases Exophiala dermatitidis Pneumonia Chronic cough Bronchoalveolar lavage 030228 respiratory system 030220 oncology & carcinogenesis medicine.symptom business medicine.drug |
| Zdroj: | Respirology Case Reports, Vol 9, Iss 6, Pp n/a-n/a (2021) Respirology Case Reports |
| ISSN: | 2051-3380 |
| Popis: | Exophiala dermatitidis is a black fungus that rarely causes respiratory infection. We report a case of E. dermatitidis pneumonia with bronchiectasis that relapsed after 11 months of voriconazole (VRCZ) treatment in a rheumatoid arthritis (RA) patient with bronchiectasis. A 65‐year‐old woman with RA and abnormal findings on chest radiography was referred for assessment of chronic cough and increased sputum production. She underwent bronchoscopy, and E. dermatitidis was identified from bronchoalveolar lavage fluid (BALF). Exophiala dermatitidis chronic lower respiratory tract infection and pneumonia were diagnosed. Although her condition improved after 11 months of VRCZ treatment, chest computed tomography (CT) images showed worsening at five months after the cessation of VRCZ treatment and E. dermatitidis was again detected in BALF. Re‐administration of VRCZ for two years improved symptoms and chest CT images, and her condition is currently stable. In patients with bronchiectasis, E. dermatitidis pneumonia might require prolonged antifungal treatment. Exophiala dermatitidis pneumonia with bronchiectasis required prolonged voriconazole treatment. |
| Databáze: | OpenAIRE |
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