Validity of dual‐energy x‐ray absorptiometry for estimation of visceral adipose tissue and visceral adipose tissue change after surgery‐induced weight loss in women with severe obesity

Autor: Maxine Ashby‐Thompson, Stanley Heshka, Bridgette Rizkalla, Rosalie Zurlo, Thaisa Lemos, Isaiah Janumala, Bret Goodpaster, James DeLany, Anita Courcoulas, Gladys Strain, Alfons Pomp, Patrick Kang, Susan Lin, John Thornton, Dympna Gallagher
Rok vydání: 2022
Předmět:
Zdroj: Obesity. 30:1057-1065
ISSN: 1930-739X
1930-7381
DOI: 10.1002/oby.23415
Popis: Reliable and simple methods to quantify visceral adipose tissue (VAT) and VAT changes are needed. This study investigated the validity of dual-energy x-ray absorptiometry (DXA) compared with magnetic resonance imaging (MRI) for estimating VAT cross sectionally and longitudinally after surgery-induced weight loss in women with severe obesity.Women with obesity (n = 36; mean age 43 [SD 10] years; 89% White) with DXA and MRI before bariatric surgery (T0) at 12 (T12) and 24 months (T24) post surgery were included. CoreScan (GE Healthcare, Chicago, Illinois) estimated VAT from 20% of the distance between the top of the iliac crest and the base of the skull. MRI VAT (total VAT) was measured from the base of the heart to the sacrum/coccyx on a whole-body scan.Mean DXA VAT was 45% of MRI VAT at T0, 46% at T12, and 68% at T24. DXA underestimated change in MRI VAT between T0 and T12 by 26.1% (0.81 kg, p = 0.03) and by 71.7% (0.43 kg, p0.001) between T12 and T24. The relationship between DXA VAT and MRI VAT differed between T12 and T24 (p value for interaction = 0.03).CoreScan lacks validity for comparing VAT across individuals or for estimating the size of changes within individuals; however, within the limits of measurement error, it may provide a useful indicator of whether some VAT change has occurred within an individual.
Databáze: OpenAIRE
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