Pharmacological interventions for drug-using offenders: an update to a systematic review and meta-analysis
Autor: | Catherine Hewitt, Julie Glanville, Amanda Perry, Kath Wright, Shilpi Swami, Lucy Burns, Marrissa Martyn-St James, Caroline Pearson, Anne Aboaja, M. Bunney, P. Thakkar, K. M. S. Kumar |
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Rok vydání: | 2021 |
Předmět: |
Drug
medicine.medical_specialty media_common.quotation_subject Psychological intervention 030508 substance abuse Naltrexone 03 medical and health sciences 0302 clinical medicine Pharmacological interventions Meta-analysis medicine 030212 general & internal medicine 0305 other medical science Adverse effect Psychiatry Law Methadone medicine.drug media_common Buprenorphine |
Zdroj: | Journal of Experimental Criminology. 18:439-495 |
ISSN: | 1572-8315 1573-3750 |
DOI: | 10.1007/s11292-020-09453-8 |
Popis: | Abstract This updated systematic review assesses the effects of pharmacological interventions for drug-using offenders. Methods Systematic review protocols and conventions of the Cochrane Collaboration were followed to identify eligible studies. Studies were pooled in a meta-analysis to assess the impact of pharmacological interventions on drug use and criminal activity. An economic appraisal was conducted. Results The search strategies identified 22 studies containing 4372 participants. Meta-analyses revealed a small statistically significant mean difference favouring pharmacological interventions relative to psychological interventions in reducing drug use and criminal activity. When comparing the drugs to one another there were no significant differences between those included (methadone versus buprenorphine, naltrexone and cyclazocine). Conclusion Overall, the findings of this review suggest that methadone and naltrexone may have some impact on reducing drug use and reincarceration. Individual pharmacological drugs had differing (generally non-significant) effects. One study identified serious adverse events. Three studies reported cost and consequences information sufficient to conduct a full economic analysis but this was not comprehensive enough to be able to make judgements across all treatment options. Full economic analyses should be encouraged. The study findings were limited mainly to male adult offenders. |
Databáze: | OpenAIRE |
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