Multifocal Conduction Block in a Patient with Sarcoid Neuropathy: Successful Treatment with Intravenous Immunoglobulin
| Autor: | Yu Kono, Renpei Sengoku, Kiyoharu Inoue, Shusaku Omoto, Masahiro Sonoo, Soichiro Mochio, Hiroshi Yaguchi |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Weakness Sarcoidosis Sensory Receptor Cells Prednisolone Neural Conduction Electromyography Diagnosis Differential Polyneuropathies hemic and lymphatic diseases Internal Medicine medicine Sarcoid neuropathy Humans Paresthesia Mobility Limitation Leg Hand Strength Reflex Abnormal biology medicine.diagnostic_test business.industry Immunoglobulins Intravenous Polyradiculoneuropathy Recovery of Function General Medicine Middle Aged medicine.disease Surgery Polyradiculoneuropathy Chronic Inflammatory Demyelinating Arm biology.protein Nerve conduction study Female medicine.symptom Antibody business Immunosuppressive Agents |
| Zdroj: | Internal Medicine. 52:999-1002 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.52.7788 |
| Popis: | A 54-year-old-woman with sarcoidosis presented with progressive symmetric, predominantly distal weakness and sensory dysfunction with areflexia in all four limbs. Nerve conduction studies showed multifocal conduction blocks in several nerves. Oral steroids were ineffective; however, intravenous immunoglobulin (IVIG) therapy rapidly and repeatedly improved the patient's neurologic symptoms with a resolution of the conduction blocks. Multifocal conduction blocks are not frequently reported in patients with sarcoid neuropathy, but they may respond to early treatment with IVIG. |
| Databáze: | OpenAIRE |
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