Non-rigid registration of serial section images by blending transforms for 3D reconstruction

Autor: Haruyuki Makishima, Takehiro Kajihara, Takahito Aoto, Shigehito Yamada, Hiroyuki Kubo, Takuya Funatomi, Yasuhiro Mukaigawa
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Pattern Recognition. 96
ISSN: 0031-3203
Popis: In this research, we propose a novel registration method for three-dimensional (3D) reconstruction from serial section images. 3D reconstructed data from serial section images provides structural information with high resolution. However, there are three problems in 3D reconstruction: non-rigid deformation, tissue discontinuity, and accumulation of scale change. To solve the non-rigid deformation, we propose a novel non-rigid registration method using blending rigid transforms. To avoid the tissue discontinuity, we propose a target image selection method using the criterion based on the blending of transforms. To solve the scale change of tissue, we propose a scale adjustment method using the tissue area before and after registration. The experimental results demonstrate that our method can represent non-rigid deformation with a small number of control points, and is robust to a variation in staining. The results also demonstrate that our target selection method avoids tissue discontinuity and our scale adjustment reduces scale change.
複数のスライスされた標本から元の立体形状を復元する画像処理技術を開発 --ヒトの成長過程の解明にも寄与--. 京都大学プレスリリース. 2019-08-02.
Databáze: OpenAIRE