WA8242A1, A2 and B, Novel Secretory Phospholipase A2 Inhibitors Produced by Streptomyces violaceusniger. I. Taxonomy, Production and Purification
| Autor: | Masanori Okamoto, Yasuhisa Tsurumi, Masakuni Okuhara, Seiji Yoshimura, Yuko Muramatsu, Takanao Otsuka, Hiroshi Hatanaka, Seiji Hashimoto |
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| Rok vydání: | 1998 |
| Předmět: |
Pharmacology
chemistry.chemical_classification biology Streptomycetaceae Adipates biology.organism_classification Phospholipases A Streptomyces In vitro Phospholipases A2 Phospholipase A2 Enzyme Biochemistry chemistry Enzyme inhibitor Drug Discovery biology.protein Actinomycetales Enzyme Inhibitors 2-Aminoadipic Acid Mycelium Bacteria |
| Zdroj: | The Journal of Antibiotics. 51:1-7 |
| ISSN: | 1881-1469 0021-8820 |
| DOI: | 10.7164/antibiotics.51.1 |
| Popis: | WA8242A1, A2 and B, novel inhibitors of secretory phospholipase A2, were obtained from the cultured mycelium of Streptomyces violaceusniger No. 8242. WA8242A1, A2 and B are structurally related compounds with α-aminoadipic acid and with various length of alkyl chains. |
| Databáze: | OpenAIRE |
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