Alcohol can inhibit effect of IL-4 on activated murine B cells
| Autor: | Linda M Pratt, Marlene Aldo-Benson, Joyce Hardwick |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Lipopolysaccharides
Immunology Thymus Gland Lymphocyte Activation Mice chemistry.chemical_compound Animals Secretion Interleukin 4 B-Lymphocytes Mice Inbred BALB C Ethanol biology Cell growth Interleukin Cell Differentiation Molecular biology In vitro Biochemistry Immunoglobulin class switching chemistry Immunoglobulin G biology.protein Interleukin-2 Interleukin-4 Antibody Spleen |
| Zdroj: | Immunologic Research. 11:117-124 |
| ISSN: | 1559-0755 0257-277X |
| Popis: | Ethanol addition to B lymphocytes in vitro inhibits antigen-induced antibody secretion and antigen-induced cell proliferation. We tested the hypothesis that ethanol can inhibit the effect of interleukins on B-cell proliferation by adding ethanol to in vitro functional assays for IL-2 and IL-4. Ethanol does not inhibit IL-2-induced B-cell differentiation, but it does inhibit IL-4-induced B-cell proliferation and IL-4-induced Ig class switching. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink