Using computational methods to design patient-specific electrospun cardiac patches for pediatric heart failure

Autor:	Benjamin W. Streeter, Milton E. Brown, Preety Shakya, Hyun-Ji Park, Jichuan Qiu, Younan Xia, Michael E. Davis
Rok vydání:	2021
Předmět:	Heart Defects Congenital Heart Failure Heart Ventricles Multipotent Stem Cells Biophysics Cell- and Tissue-Based Therapy Bioengineering Rats Biomaterials Mechanics of Materials Ceramics and Composites Animals Humans Child
Zdroj:	Biomaterials. 283
ISSN:	1878-5905
Popis:	Autologous cardiac cell therapy is a promising treatment for combating the right ventricular heart failure (RVHF) that can occur in patients with congenital heart disease (CHD). However, autologous cell therapies suffer from low cell retention following injection and patient-to-patient variability in cell quality. Here, we demonstrate how computational methods can be used to identify mechanisms of cardiac-derived c-Kit
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a9c6820e3df168561a0fdfdbaa5f77 https://pubmed.ncbi.nlm.nih.gov/35219147 Zobrazit plný text záznamu Full Text from ScienceDirect