Spurious Uptake on 68Ga–Prostate-Specific Membrane Antigen PET/CT Due to Ankylosing Spondylitis; A Rare Pitfall in Imaging of Biochemical Recurrence of Prostate Cancer
| Autor: | Afshin Nasoodi, Ciaran Johnston, Roisin M Heaney |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
Biochemical recurrence medicine.medical_specialty Radiography Gallium Radioisotopes urologic and male genital diseases 030218 nuclear medicine & medical imaging 03 medical and health sciences Prostate cancer 0302 clinical medicine Recurrence Positron Emission Tomography Computed Tomography Glutamate carboxypeptidase II Humans Medicine Spondylitis Ankylosing Radiology Nuclear Medicine and imaging Edetic Acid Gallium Isotopes Sacroiliac joint PET-CT Ankylosing spondylitis business.industry Sacroiliitis Prostatic Neoplasms Biological Transport General Medicine Middle Aged medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis Radiology business Oligopeptides |
| Zdroj: | Clinical Nuclear Medicine. 46:e373-e375 |
| ISSN: | 1536-0229 0363-9762 |
| DOI: | 10.1097/rlu.0000000000003616 |
| Popis: | Bone is one of the most common sites of prostate cancer recurrence, and 68Ga-prostate-specific membrane antigen (PSMA) uptake by benign bone entities poses a diagnostic dilemma. We describe the case of a 60-year-old man with recurrence in a small presacral node on 68Ga-PSMA PET/CT. Of note, the images also demonstrated bilateral asymmetrical sacroiliac joint uptake. A history of ankylosing spondylitis was subsequently elicited, confirming the radiographic suspicion of sacroiliitis, therefore confirming the nonmalignant nature of 68Ga-PSMA uptake related to sacroiliitis rather than osseous recurrence from prostate carcinoma. 68Ga-PSMA uptake may indicate angioneogenesis in sacroiliitis and consequently may be helpful in assessing disease activity and therapy response. |
| Databáze: | OpenAIRE |
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