Recent infections among newly diagnosed cases of HIV infection in Spain, 2015–2016. National estimates using cohort data
| Autor: | Inma Jarrín, Alvaro Mena, Angels Jaen, Victoria Hernando, María Teresa Cuevas, Mar Vera, Maria Tasias, Maria Teresa Pérez-Olmeda, CoRIS-HIV Biobank, Asunción Díaz |
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| Rok vydání: | 2021 |
| Předmět: |
Male
0301 basic medicine Microbiology (medical) Pediatrics medicine.medical_specialty 030106 microbiology Coris Human immunodeficiency virus (HIV) HIV Infections Newly diagnosed medicine.disease_cause Sexual and Gender Minorities 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) medicine Humans 030212 general & internal medicine Homosexuality Male General Immunology and Microbiology biology business.industry General Medicine medicine.disease biology.organism_classification CD4 Lymphocyte Count Infectious Diseases Spain Cohort Female business Cohort study |
| Zdroj: | Infectious Diseases. 53:440-449 |
| ISSN: | 2374-4243 2374-4235 |
| Popis: | To estimate the prevalence of recent infection (RI) among people newly diagnosed with HIV in Spain using a representative sample collected by the AIDS Research Network cohort (CoRIS) during 2015-2016.Stratified sampling of CoRIS data was used with proportional allocation by mode of transmission of new HIV diagnoses notified to National Surveillance System. Samples used were from patients in the CoRIS cohort with available stored plasma collected within 6 months after diagnosis. Weighted methods were used to estimate the prevalence of RI and multivariate logistic regression models were used to determine associated factors.Of the 669 individuals included, 55.1% were men who had sex with men (MSM), 24.6% were heterosexual, and 20.3% were non-MSM non-heterosexual. The weighted prevalence of RI was 11.8% (95% Confidence interval [CI] 9.4-14.8%) overall, 15.5% (12.2-19.4%) among MSM, 6.3% (3.9-10.0%) among heterosexual, and 8.6% (3.2-20.9%) in non-MSM non-heterosexual persons. Factors associated with prevalence of RI were: MSM (OR 2.05; 95% CI 1.02-4.14)In the absence of direct data from surveillance systems, the use of cohort data is a very valuable option for identifying the prevalence of RI at national level. This is the first nationwide study carried out in Spain to determine the prevalence of RI using an avidity assay. |
| Databáze: | OpenAIRE |
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