Bizarre parosteal osteochondromatous proliferation or Nora’s lesion affecting the extremities: A concise update

Autor: Dharmshaktu, Ganesh Singh, Dharmshaktu, Ishwar Singh, Pangtey, Tanuja
Rok vydání: 2022
DOI: 10.6084/m9.figshare.21345006
Popis: Bizarre parosteal osteochondromatous proliferation (BPOP) was first described in 1983 by Nora et al. with cases involving hands and feet.[1] Therefore, this clinical entity is also called Nora’s lesion. Localized swelling and pain are the most common presentations. The radiographic findings include dense and mineralized lesions adjacent to an uninvolved bone. Hand and feet are the most commonly involved sites, but other anatomical locations have also been reported over the years. Various disorders pose diagnostic challenges and need to be kept in the working diagnoses [Table 1]. However, osteochondroma is the most common resembling lesion that must be excluded from the study. BPOP usually bears no connection with the adjacent bone. BPOP is considered a locally aggressive benign tumor that usually affects the age range of 8–74 years, as mentioned in the literature. The involvement in the younger age group is not infrequent. There were three cases (between ages 2 and 12 years) in a recent series.[2] Reports of involvement in the age group beyond above-mentioned limits were also noted during the literature search for this article, with two cases of age 3 years reported [Table 2]. The age of involvement is thus wider ranging in cases of BPOP. A retrospective analysis of cases of BPOP from the Scottish Bone Tumor Registry from 1983 to 2009 revealed only 13 cases with no gender predilection (six males and seven females) and a wide age range (13–65 years). Twelve of these cases involved hands and feet and one case involved tibial tuberosity.[3] A previous history of trauma was noted only in two cases. There was no metastasis associated, but recurrence in the range of 50% was noted.
Databáze: OpenAIRE