Pseudo-insular glioma syndrome: illustrative cases
| Autor: | Alexander F. Haddad, Jacob S. Young, Ramin A. Morshed, S. Andrew Josephson, Soonmee Cha, Mitchel S. Berger |
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| Rok vydání: | 2021 |
| Předmět: |
ANA = antinuclear antibodies
CT = computed tomography MCA = middle cerebral artery LGG = lower-grade glioma PET = positron emission tomography FLAIR = fluid-attenuated inversion recovery Rare Diseases MS = multiple sclerosis Clinical Research DWI = diffusion-weighted imaging mimic vasculopathy Cancer PACNS = primary angiitis of the central nervous system low-grade glioma CNS = central nervous system DTI = diffusion tensor imaging Neurosciences imaging General Medicine Brain Disorders Brain Cancer MRI = magnetic resonance imaging MR = magnetic resonance Biomedical Imaging CSF = cerebrospinal fluid PWI = perfusion-weighted imaging MRI TDL = tumefactive demyelinating lesion |
| Zdroj: | Journal of neurosurgery. Case lessons, vol 2, iss 26 |
| Popis: | BACKGROUND Lower-grade insular gliomas often appear as expansile and infiltrative masses on magnetic resonance imaging (MRI). However, there are nonneoplastic lesions of the insula, such as demyelinating disease and vasculopathies, that can mimic insular gliomas. OBSERVATIONS The authors report two patients who presented with headaches and were found to have mass lesions concerning for lower-grade insular glioma based on MRI obtained at initial presentation. However, on the immediate preoperative MRI obtained a few weeks later, both patients had spontaneous and complete resolution of the insular lesions. LESSONS Tumor mimics should always be in the differential diagnosis of brain masses, including those involving the insula. The immediate preoperative MRI (within 24–48 hours of surgery) must be compared carefully with the initial presentation MRI to assess interval change that suggests tumor mimics to avoid unnecessary surgical intervention. |
| Databáze: | OpenAIRE |
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