Comparison of Umbilical Cord Interlukin-8 in Low Birth Weight Infants with Premature Rupture of Membranes and Intact Membranes
| Autor: | M Rafeey, Taghy Melekian, N Najati |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Fetal Membranes Premature Rupture medicine.medical_specialty Extraembryonic Membranes Gestational Age Prom Umbilical cord Sepsis Obstetrics and gynaecology Pregnancy medicine Humans Blood culture medicine.diagnostic_test Neonatal sepsis business.industry Obstetrics Interleukin-8 Infant Newborn Infant Low Birth Weight Fetal Blood medicine.disease female genital diseases and pregnancy complications Low birth weight medicine.anatomical_structure Case-Control Studies Female medicine.symptom business Agronomy and Crop Science Premature rupture of membranes |
| Zdroj: | Pakistan Journal of Biological Sciences. 12:1094-1097 |
| ISSN: | 1028-8880 |
| DOI: | 10.3923/pjbs.2009.1094.1097 |
| Popis: | Some studies showed increased levels ofproinflammatory cytokines like IL-6, IL-8 and TNF-alpha in the blood samples of pregnant women with PROM (Premature rupture of membranes) and their neonates. The aim of this study was to find a relationship between increased level of IL-8 and PROM, a cost benefit method for early diagnosis and reduction of hospitalization period of neonatal sepsis. This case control study was conducted in Obstetrics and Gynecology Department of Al-Zahra Hospital at Tabriz University of Medical Sciences, Iran from 10th April 2001 to 20th June 2003. We studied 50 LBW (Low birth weight) neonates born from mothers with PROM as the case group and fifty LBW neonates born from mothers without PROM as our control group Neonates born from pregnant women with PROM underwent sepsis workup and blood samples from their umbilical cord were sent for blood culture and IL-8 level measurement. Mean levels of IL-8 in study and control groups were 128.12 and 39.2 pg mL(-1), respectively. We had no positive blood culture and no bacteria could be isolated. Significantly elevated values (p |
| Databáze: | OpenAIRE |
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