Pancytopenia and Colitis with Clostridium difficile in a Rheumatoid Arthritis Patient Taking Methotrexate, Antibiotics and Non-steroidal Anti-inflammatory Drugs
| Autor: | Shigeru Kotake, M Tomii, Naoyuki Kamatani, Yuki Nanke, Akama H |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty Pancytopenia medicine.drug_class Antibiotics Arthritis Gastroenterology Arthritis Rheumatoid Rheumatology immune system diseases Internal medicine Humans Medicine Drug Interactions heterocyclic compounds Colitis skin and connective tissue diseases Enterocolitis Pseudomembranous Aged Enterocolitis Clostridioides difficile business.industry Anti-Inflammatory Agents Non-Steroidal General Medicine Clostridium difficile medicine.disease Anti-Bacterial Agents Methotrexate Rheumatoid arthritis Immunology Female medicine.symptom business medicine.drug |
| Zdroj: | Clinical Rheumatology. 20:73-75 |
| ISSN: | 0770-3198 |
| Popis: | Methotrexate (MTX) is widely used despite its side-effects. We describe a rheumatoid arthritis (RA) patient taking low-dose MTX who developed severe pancytopenia and colitis with Clostridium difficile after the administration of antibiotics for acute pyelonephritis. Our case suggests that low-dose MTX may seriously interact with antibiotics and that these side-effects should always be considered when RA patients are treated with MTX and antibiotics. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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