Differential size distribution of atrial dense granules in spontaneously hypertensive, Wistar-Kyoto and Wistar rats
| Autor: | G. Norton, I. Katzeff, G De Wet, C. Rosendorff, B.A. Stein |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Histology business.industry Rats Inbred Strains Cytoplasmic Granules Rats Inbred WKY Rats Wistar kyoto Microscopy Electron Endocrinology Internal medicine Rats Inbred SHR cardiovascular system medicine Distribution (pharmacology) Animals cardiovascular diseases Wistar Kyoto Rats Heart Atria Anatomy business circulatory and respiratory physiology |
| Zdroj: | Acta anatomica. 137(4) |
| ISSN: | 0001-5180 |
| Popis: | The differential size distribution of atrial dense granules (ADGs) in spontaneously hypertensive rats (SHR) and two normotensive controls, Wistar and Wistar-Kyoto (WKY) rats, was investigated. The ADGs in SHR were smaller than those in Wistar rats. The ADGs of WKY rats were of intermediate size. It is possible that ADGs are more rapidly secreted in SHR compared with WKY and Wistar rats or that the smaller-diameter granules may contain more atriopeptinogen than the larger granules. The intermediate size of the ADGs in WKY suggests that the WKY variant is morphologically intermediate between the SHR and Wistar strains. |
| Databáze: | OpenAIRE |
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