Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression

Autor: Yu Li, Christian Weber, Judith C. Sluimer, Jacob F. Bentzon, Andreas Ludwig, Marjo M. P. C. Donners, Thomas L. Theelen, Marion J.J. Gijbels, Joerg W. Bartsch, Jack P.M. Cleutjens, Yvonne Jansen, Erik A.L. Biessen, Emiel P. C. van der Vorst, Erwin Wijnands, Kosta Theodorou, Mike L. J. Jeurissen, Ine M. J. Wolfs
Přispěvatelé: Pathologie, RS: CARIM - R3.06 - The vulnerable plaque: makers and markers, Moleculaire Genetica, Promovendi CD, MUMC+: DA CDL Algemeen (9), RS: NUTRIM - R2 - Liver and digestive health, RS: NUTRIM - R2 - Gut-liver homeostasis, Biochemie, RS: CARIM - R3.07 - Structure-function analysis of the chemokine interactome for therapeutic targeting and imaging in atherosclerosis, CARIM PhD-award, Deutsche Forschungsgemeinschaft (Alemania), Alexander von Humboldt-Stiftung, AII - Inflammatory diseases, ACS - Atherosclerosis & ischemic syndromes, Medical Biochemistry
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
Genetically modified mouse
Pathology
medicine.medical_specialty
lcsh:Medicine
030204 cardiovascular system & hematology
Biology
Granulocyte
PERIPHERAL-BLOOD
METALLOPROTEASE-DISINTEGRIN ADAM8
DENDRITIC CELLS
Article
Lesion
03 medical and health sciences
0302 clinical medicine
Immune system
Antigens
CD
medicine
Animals
Humans
MACROPHAGES
lcsh:Science
TUMOR-NECROSIS-FACTOR
Mice
Knockout
TRANSGENIC MICE
Metalloproteinase
Multidisciplinary
Gene Expression Profiling
lcsh:R
Membrane Proteins
Atherosclerosis
Immunohistochemistry
TNF-ALPHA
Plaque
Atherosclerotic
Mice
Inbred C57BL
ADAM Proteins
Haematopoiesis
Carotid Arteries
030104 developmental biology
medicine.anatomical_structure
MYOCARDIAL-INFARCTION
Female
Tumor necrosis factor alpha
lcsh:Q
IMMUNE-SYSTEM
medicine.symptom
EXPRESSION ANALYSIS
ADAM8
Zdroj: Theodorou, K, van der Vorst, E P C, Gijbels, M J, Wolfs, I M J, Jeurissen, M, Theelen, T L, Sluimer, J C, Wijnands, E, Cleutjens, J P, Li, Y, Jansen, Y, Weber, C, Ludwig, A, Bentzon, J F, Bartsch, J W, Biessen, E A L & Donners, M M P C 2017, ' Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression ', Scientific Reports, vol. 7, 11670 . https://doi.org/10.1038/s41598-017-10549-x
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, 7:11670. Nature Publishing Group
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scientific Reports
Scientific reports 7, 11670 (2017). doi:10.1038/s41598-017-10549-x
Scientific reports, 7(1):11670. Nature Publishing Group
ISSN: 2045-2322
Popis: Scientific reports 7(1), 11670 (2017). doi:10.1038/s41598-017-10549-x
Published by Nature Publishing Group, London
Databáze: OpenAIRE
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