Clinical predictors of hyponatremia in patients with heart failure according to severity of chronic kidney disease
Autor: | Ivan Velat, Željko Bušić, Viktor Čulić |
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Rok vydání: | 2022 |
Předmět: |
Heart Failure
Dihydropyridines Receptors Angiotensin Angiotensin-Converting Enzyme Inhibitors General Medicine Calcium Channel Blockers Peptide Fragments Cardiovascular drugs Cardio-renal syndrome Cardiac failure Diuretics Angiotensin Receptor Antagonists Cross-Sectional Studies Hydrochlorothiazide Sodium Potassium Chloride Symporter Inhibitors Natriuretic Peptide Brain Humans Female Renal Insufficiency Chronic Biomarkers Hyponatremia Mineralocorticoid Receptor Antagonists |
Zdroj: | Wiener klinische Wochenschrift. 134:636-645 |
ISSN: | 1613-7671 0043-5325 |
DOI: | 10.1007/s00508-022-02040-z |
Popis: | Background: Chronic kidney disease (CKD) has been associated with adverse clinical outcomes. Hyponatremia, a marker of illness severity and poor prognosis, is commonly exhibited in patients with CKD. Methods: This cross-sectional study included patients hospitalized due to heart failure (HF). We used stepwise logistic regression to investigate the independent association of cardiovascular drugs, markers of HF severity, and baseline clinical characteristics with hyponatremia in three subgroups ; normal renal function, mild-to-moderate CKD, and severe CKD. Results: Of the 1232 patients, 38.6% were hyponatremic. Patients with severe CKD, compared to those with normal renal function and mild-to- moderate CKD, were more likely to be hyponatremic (47.1%, 34.4% and 36.6%, respectively ; p |
Databáze: | OpenAIRE |
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