Estimating the Damaging Power of High-Stress Ventilation
| Autor: | Patricia Rm Rocco, Luciano Gattinoni, John J. Marini |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Ventilator-Induced Lung Injury Lung injury Critical Care and Intensive Care Medicine law.invention 03 medical and health sciences 0302 clinical medicine Control theory law Tidal Volume Humans Medicine Lung volumes Lung Tidal volume Power density business.industry Respiration General Medicine respiratory system Respiration Artificial Power (physics) 030228 respiratory system Ventilation (architecture) business Tidal power Energy (signal processing) |
| Zdroj: | Respiratory Care. 65:1046-1052 |
| ISSN: | 1943-3654 0020-1324 |
| DOI: | 10.4187/respcare.07860 |
| Popis: | Redirection of our clinical attention from the pressures and volumes of the individual cycle to the broader and more inclusive considerations of energy load and power has untapped potential to reduce iatrogenic risk from ventilation (ie, ventilator-induced lung injury). Power is the product of breathing frequency and inflation energy per breath. Yet, while feasible to calculate at the bedside, measuring total power may not prove to be precise enough for accurate prediction of ventilator-induced lung injury, even if normalized to lung capacity (ie, specific power). The same power value can be reached by a multitude of frequency and tidal volume combinations, not all of which carry equal risk of damage. If some arbitrary level of alveolar pressure were accepted as a sharply defined hazard boundary, a rather straightforward geometric analysis theoretically would allow partitioning of overall tidal energy into components above and below a damage threshold. In this discussion, we introduce the concept of quantitative power partitioning and illustrate how tidal energy and power might be deconstructed into their key parts. |
| Databáze: | OpenAIRE |
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