Frozen-Section Tissue Processing in Mohs Surgery
| Autor: | Arif Aslam, Sumaira Z. Aasi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Quality Control
medicine.medical_specialty Skin Neoplasms Computer science medicine.medical_treatment Coloring agents Dermatology Micrographic surgery Antibodies 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Cytoreduction Surgical Procedures Mohs surgery medicine Frozen Sections Humans Tolonium Chloride Coloring Agents Frozen section procedure Margins of Excision Tissue Processing General Medicine Mohs Surgery Debulking Immunohistochemistry Review article 030220 oncology & carcinogenesis Keratins Surgery Radiology |
| Zdroj: | Dermatologic Surgery. 45:S57-S69 |
| ISSN: | 1524-4725 1076-0512 |
| DOI: | 10.1097/dss.0000000000002260 |
| Popis: | Background Mohs micrographic surgery (MMS) is the most reliable tissue-sparing technique in the management of cutaneous malignancies. Although the concept is simple, there is considerable variability in the mapping and processing techniques used by Mohs surgeons and histotechnicians. Objective This review article aims to examine the frozen-section tissue processing techniques. Existing variations will be discussed and pearls offered to optimize the frozen processing technique. Methods A PubMed search was performed for publications on methods of tissue processing in MMS. Results Our review highlights variations in debulking, embedding, processing adipose tissue, cartilage, and wedge resections. We offer pearls on how to avoid false-positive and false-negative margins and discuss advances in immunohistochemistry. Conclusion Our article provides a how-to format on the different stages of tissue processing with pearls and techniques to optimize practice and improve accuracy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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