Primary diffuse leptomeningeal gliomatosis: An autopsy case report
| Autor: | Arikapadu Haritha Chowdary, Angamattu Kanikannan Meena, Rupam Borgohain, Megha S Uppin, Rukmini Mridula Kandadai, Challa Sundaram, Shaik Afshan Jabeen |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.diagnostic_test business.industry Leptomeninges Meninges neoplastic meningitis Case Report Autopsy medicine.disease Primary tumor lcsh:RC346-429 Cerebrospinal fluid medicine.anatomical_structure Glioma Biopsy medicine Chronic meningitis meningeal biopsy Neurology (clinical) Radiology leptomeningeal gliomatosis Neoplastic meningitis business lcsh:Neurology. Diseases of the nervous system |
| Zdroj: | Annals of Indian Academy of Neurology Annals of Indian Academy of Neurology, Vol 17, Iss 2, Pp 227-230 (2014) |
| ISSN: | 0972-2327 |
| DOI: | 10.4103/0972-2327.132647 |
| Popis: | Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare condition, characterized by infiltration of the meninges by glial cells without evidence of the primary tumor in the brain or spinal cord parenchyma. Glioma arising primarily from the leptomeninges is extremely rare and often diagnosed only in post mortem examination and the diagnosis may be missed in meningeal biopsy. We describe a young female who presented with symptoms of raised intracranial pressure with imaging evidence of diffuse leptomeningeal enhancement in whom autopsy confirmed the diagnosis of PDLG. Our case illustrates the diagnostic difficulties in making the pre-mortem diagnosis even with multiple cerebrospinal fluid cytologies and leptomeningeal biopsy. |
| Databáze: | OpenAIRE |
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