Variability of attitudes toward early initiation of HAART for HIV infection: A study of French prescribing physicians

Autor:	R. Landman, J. P. Moatti, V. Perrin, P. Huard
Rok vydání:	2000
Předmět:	Adult Male medicine.medical_specialty Health (social science) Social Psychology Attitude of Health Personnel Human immunodeficiency virus (HIV) HIV Infections Logistic regression medicine.disease_cause Asymptomatic Early initiation Pharmacotherapy Antiretroviral Therapy Highly Active Internal medicine medicine Humans Practice Patterns Physicians' Aged Response rate (survey) business.industry Public Health Environmental and Occupational Health virus diseases Guideline Middle Aged Viral Load CD4 Lymphocyte Count Practice Guidelines as Topic Immunology Regression Analysis Female France medicine.symptom business Viral load
Zdroj:	AIDS Care. 12:711-716
ISSN:	1360-0451 0954-0121
Popis:	This study assessed prescribing physicians' attitudes toward early initiation of HAART, three months after the dissemination of the first French official treatment guideline. Telephone interviews have been made in a national random sample of physicians with full- or part-time practice in hospital departments delivering care for HIV-infected patients. Questionnaires included hypothetical clinical cases. Logistic regression compared characteristics of respondents according to attitudes toward HAART. Among the 483 respondents (response rate = 87.0%), agreement was high with official recommendations to systematically initiate HAART with protease inhibitors (PIs) for patients with CD4+ cell countsor = 300/mm3, following a diagnosis of acute primary HIV infection, or for HIV sexual risk post-exposure prophylaxis. Confronted with a case of a naive asymptomatic patient with stable 450 CD4+/mm3, 34.6% would prescribe HAART with PIs in any case, and 29.8% only if the patient has plasma viral loador = 10,000 HIV RNA copies/ml. The remaining 35.6% would not prescribe PIs and were older, had limited activity in HIV care and expressed more interest in alternative medicines. To avoid a confusing impact of variability of clinical attitudes toward uncertainties associated with antiretroviral treatments among HIV-infected patients, shared decision-making between patient and physician should be promoted for initiation of HAART.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96c61177a6f6ff17010f1af8aa375a2 https://doi.org/10.1080/09540120020014246 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.