Members of the low density lipoprotein receptor family control diverse physiological processes

Autor:	W S Argraves
Rok vydání:	2001
Předmět:	Low-density lipoprotein receptor gene family Membrane Glycoproteins Repertoire Heymann Nephritis Antigenic Complex Kidney metabolism Biology Endocytosis Kidney Cell biology Absorption Receptors LDL LDL receptor Animals Humans lipids (amino acids peptides and proteins) Receptor
Zdroj:	Frontiers in bioscience : a journal and virtual library. 6
ISSN:	1093-9946
Popis:	The low density lipoprotein receptor (LDLR) family is a group of receptors that mediate endocytosis leading to lysosomal degradation of an enormous repertoire of ligands. To date, over 50 distinct macromolecules have been shown to bind members of the family. This wide spectrum of ligand recognition is the basis for an immense diversity in physiological processes in which these receptors participate. In this article, the physiological roles of the LDLR family members are briefly reviewed and a comprehensive list of the ligands with which the receptors interact is presented.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c969ec3cc6fd8b03925693864666b028 https://pubmed.ncbi.nlm.nih.gov/11229868 Zobrazit plný text záznamu