Usefullness of peak mitral regurgitation velocity to left ventricular outflow tract time velocity integral ratio as a new prognostic marker for one year and long term mortality in failing heart
| Autor: | Kevser Gülcihan Balci, Ozcan Ozeke, Mehmet Serkan Cetin, F Unal, Firat Ozcan, Serkan Topaloglu, Dursun Aras, Firdevs Aysenur Ekizler, Mehmet Akif Erdöl, A. Temizhan, E.H. Ozcan Cetin, Serkan Cay, B Tekin Tak |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Web of Science |
| ISSN: | 1522-9645 0195-668X |
| Popis: | Background and aim Systemic vascular resistance (SVR) is useful for risk estimation and therapy guidance in HF. It has been showed that the ratio of peak mitral regurgitation velocity (MRV) to left ventricular outflow tract velocity-time integral (LVOT VTI) correlated positively with SVR. We aimed to assess the association of MRV/LVOT VTI ratio with established prognostic markers and its prognostic role for predicting one year and long term composite end-points in patients with HF and reduced ejection fraction (HFrEF). Material and methods We prospectively enrolled a total of 72 patients with HFrEF and 10 control subjects. Patients were followed up patients for median 40.5 months. Primary composite endpoint (CEP) was defined as any of these outcomes including requiring mechanical circulatory support, cardiac transplantation and all-cause mortality. Results CEP(+) patients had higher MRV/LVOT VTI ratio than others (0.48±0.15 vs. 0.39±0.18 p=0.012). MRV/LVOT VTI ratio was positively correlated with functional status (β=0.539, p=0 Conclusion MRV/LVOT VTI ratio seemed to be useful predictor of poor prognosis associated with other established HF prognostic markers. Figure 1 Funding Acknowledgement Type of funding source: None |
| Databáze: | OpenAIRE |
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