Laparoscopic surgical exploration is an effective strategy for locating occult primary neuroendocrine tumors
| Autor: | Kristen P. Massimino, Esther Han, Rodney F. Pommier, Su Ellen J. Pommier |
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| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Colonoscopy Neuroendocrine tumors law.invention Bronchoscopy Capsule endoscopy law medicine Humans Laparoscopy Retrospective Studies medicine.diagnostic_test business.industry Magnetic resonance imaging Retrospective cohort study General Medicine Middle Aged medicine.disease Occult Surgery Neuroendocrine Tumors Neoplasms Unknown Primary Female Radiology business |
| Zdroj: | American journal of surgery. 203(5) |
| ISSN: | 1879-1883 |
| Popis: | Background Many patients with neuroendocrine tumors (NETs) have metastases at diagnosis. Despite extensive metastases the primary tumors remain small and difficult to locate. Methods Records of patients diagnosed with metastatic abdominal NETs from 2006 to 2010 were reviewed retrospectively. Results of preoperative imaging, procedures, and surgical explorations were compared for their efficacy at finding primary tumors. Results Sixty-three patients were identified. Seventeen percent (11 of 63) of tumors were located by preoperative testing. The sensitivities of preoperative colonoscopy (23% [n = 26]), computed tomography scan (6.7% [n = 60]), and somatostatin receptor scintigraphy (2.0% [n = 52]) were low. No tumors were found by magnetic resonance imaging (n = 9), upper endoscopy (n = 24), capsule endoscopy (n = 2), or bronchoscopy (n = 4). Surgical exploration was the most sensitive (79% [n = 63]) method of tumor detection. Seventy-two percent of surgical localizations were laparoscopic. Conclusions Surgical exploration was superior to all other modalities for locating primary NETs. Laparoscopy had a high probability of finding occult primary neuroendocrine tumors. |
| Databáze: | OpenAIRE |
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